This work is designed to answer both sceptical attacks on knowledge and epistemological relativism implied in the sceptic’s position. Rather than following the traditional path of developing a foundations picture along either rationalist or empiricist lines, Harrison turns to the resources of pure reason alone to repel the sceptic’s attacks and to find that about which we can be certain. Since the sceptic’s arguments "have been produced by reason, it is important if reason is going to be considered trustworthy that (...) they can also be answered by reason." Harrison’s thesis is that by reason alone "standards that judgments have to match up to if they are going to be thought of as judgments about the world" can be found. Such standards can be produced by an "inquiry into the essential conditions of our world being a comprehensible world.". (shrink)

While Hirst provides valuable insights into the thought of Bernard and of Durkheim, especially The Rules of Sociological Method, he does not attempt a full explanation of either man's thought. His goal is broader than that. Hirst's purpose in this book is "... to question and to challenge the dominant conceptions of epistemology in sociology.".

In this work Pollock attempts to recast the epistemological enterprise. Traditional epistemology has been centered on the search for truth conditions. It has been assumed that unless these are found the sceptic’s attack on knowledge claims cannot be conclusively answered. Pollock contends that traditional epistemologists have been barking up the wrong tree. The problem of epistemology is not to prove the trustworthiness of the justification condition. The proper task of epistemologists is to reveal the logical connection between the source of (...) our knowledge and the knowledge the source provides. This is to be done through an analysis of the meaning of statements, and the meaning of a statement is determined by the "justification conditions of it and its denial." Epistemological issues, such as perception, other minds, historical knowledge, a priori knowledge, amount to "nothing more than describing the justification conditions for statements in the different areas of knowledge." But, then what is meant by "justification conditions"? (shrink)

In the past 300 years philosophy has been preoccupied with the problem of knowledge. Since Descartes, traditional, prescientific culture has eroded under the sceptical attack and has been replaced by a new culture characterized by an unprecedented growth in scientific knowledge and its powerful models of explanation. Gellner seeks to understand "the differences between its two shores, the nature of the reasons and causes which explain or justify our firm location on one side of it." His concern is with relativism, (...) not only how to state the problem, but also how to find norms independent of any belief system which would codify or justify one system rather than another one. What this comes to is the legitimation of belief, the search for and use of final norms which are legitimate prior to any specific information about the world and serve as the final court of appeal for all study. This he claims is the central problem of the theory of knowledge. (shrink)

This work is designed to answer both sceptical attacks on knowledge and epistemological relativism implied in the sceptic’s position. Rather than following the traditional path of developing a foundations picture along either rationalist or empiricist lines, Harrison turns to the resources of pure reason alone to repel the sceptic’s attacks and to find that about which we can be certain. Since the sceptic’s arguments "have been produced by reason, it is important if reason is going to be considered trustworthy that (...) they can also be answered by reason." Harrison’s thesis is that by reason alone "standards that judgments have to match up to if they are going to be thought of as judgments about the world" can be found. Such standards can be produced by an "inquiry into the essential conditions of our world being a comprehensible world.". (shrink)

The purpose of this book is to lay to rest "fruitless controversy over mind and body" by developing a comprehensive theory of mind. The theory Matson argues for is mind-body identity. In developing his position he takes a hard materialist line: "... if sensations are brain processes then they cannot be... anything else." Yet, he asks, "What is the sentience? Why is there any such phenomenon? What difference does it make?" Rejecting dualism, he steers his materialist identity theory between two (...) mires: epiphenomenalism and behaviorism. His contention is that while sensations are brain processes, man is a sentient being and that sentience makes a difference. The difference sentience makes allows us to say that man is not a machine and is free. (shrink)

We analyze the rather unusual properties of some exact solutions in 2D dilaton gravity for which infinite quantum stresses on the Killing horizon can be compatible with regularity of the geometry. In particular, the Boulware state can support a regular horizon. We show that such solutions are contained in some well-known exactly solvable models (for example, RST). Formally, they appear to account for an additional coefficient B in the solutions (for the same Lagrangian which contains also “traditional” solutions) that gives (...) rise to the deviation of temperature T from its Hawking value T H . The Lorentzian geometry, which is a self-consistent solution of the semiclassical field equations, in such models, is smooth even at B≠0 and there is no need to put B=0 (T=T H ) to smooth it out. We show how the presence of B≠0 affects the structure of spacetime. In contrast to “usual” black holes, full fledged thermodynamic interpretation, including definite value of entropy, can be ascribed (for a rather wide class of models) to extremal horizons, not to nonextreme ones. We find also new exact solutions for “usual” black holes (with T=T H ). The properties under discussion arise in the weak-coupling regime of the effective constant of dilaton-gravity interaction. Extension of features, traced in 2D models, to 4D dilaton gravity leads, for some special models, to exceptional nonextreme black holes having no own thermal properties. (shrink)

I agree with Oaksford & Chater (O&C) that human beings resemble Bayesian reasoners much more closely than ones engaging standard logic. However, I have many problems with their framework, which appears to be rooted in normative rather than ecological rationality. The authors also overstate everyday rationality and neglect to account for much relevant psychological work on reasoning.

Research papers presented at the same title scientific conference, dedicated to the World Philosophy Day.

O presente artigo objetiva apresentar uma compreensão crítica do tempo presente, que se pode chamar de contemporaneidade. Nessa direção, as reflexões sobre esse momento histórico priorizaram os questionamentos filosóficos de Heidegger. Para interpretação mais ampla do pensamento heideggeriano, foi abordada, rapidamente, as concepções existenciais de homem e de mundo trazidas em sua obra “Ser e tempo”. Após essas considerações, a “Era da Técnica”, marcada pelo esquecimento do ser, foi tomada enquanto foco de discussão. Por fim, ressalta-se a inquietação não com (...) relação ao crescimento da técnica planetária, mas sim acerca do fato de o homem não compreender a dimensão e o sentido das transformações empreendidas por esta destinação; rejeitando, com isso, aquilo que tem de mais próprio, a condição de ser o único ser que reflete. (shrink)

The focus of this study was to analyze the content, distribution, and comparative genome relationships of 996 chromosome bin-mapped expressed sequence tags accounting for 2266 restriction fragments on the homoeologous group 3 chromosomes of hexaploid wheat. Of these loci, 634, 884, and 748 were mapped on chromosomes 3A, 3B, and 3D, respectively. The individual chromosome bin maps revealed bins with a high density of mapped ESTs in the distal region and bins of low density in the proximal region of the (...) chromosome arms, with the exception of 3DS and 3DL. These distributions were more localized on the higher-resolution group 3 consensus map with intermediate regions of high-mapped-EST density on both chromosome arms. Gene ontology classification of mapped ESTs was not significantly different for homoeologous group 3 chromosomes compared to the other groups. A combined analysis of the individual bin maps using 537 of the mapped ESTs revealed rearrangements between the group 3 chromosomes. Approximately 232 of the consensus mapped ESTs matched sequences on rice chromosome 1 and revealed large- and small-scale differences in gene order. Of the group 3 mapped EST unigenes ∼21 and 32% matched the Arabidopsis coding regions and proteins, respectively, but no chromosome-level gene order conservation was detected. (shrink)

J B O O’Malley; Style and Education, Journal of Philosophy of Education, Volume 1, Issue 1, 30 May 2006, Pages 19–28, https://doi.org/10.1111/j.1467-9752.1967.t.

This paper argues that professionals who make boundary-related decisions should be guided by relationship-based practice. In our roles as service users and professionals, drawing from our lived experiences of professional relationships, we argue we need to move away from distance-based practice. This includes understanding the boundary stories and narratives that exist for all of us – including the people we support, other professionals, as well as the organisations and systems within which we work. When we are dealing with professional boundary (...) issues, we should centre relationship-building skills that are central to many other aspects of our work. Skills that foster relationships at all levels – between professionals, service users, and services – need to be revalued. Our final recommendation is to create, develop, and foster safer spaces within and outside of organisations, as well as inter-professionally, for the discussion and exploration of boundary-related issues and practice. We are interested in hearing from those with experiences of being marginalised by boundaries so that they can inform a reshaping of our collective ideas around boundary related practices. To foster relationship-based practices in organisations, we have outlined several recommendations here; however, we recognize that these do not go far enough, and that collective action is needed to inform systemic change. (shrink)

The aim of the present investigation was to describe and to classify significant ethical problems encountered by the members of the staff during the daily clinical work at a hospital medical department. A set of definitions was prepared for the purpose, including the definition of a 'significant ethical problem'. During a three month period 426 inpatients and 173 outpatients were admitted. Significant ethical problems were encountered during the management of 106 in-patients (25 per cent) and 9 out-patients (5 per cent). (...) No significant difference was found between the frequency of ethical problems in female and male patients, but a positive correlation was noted between the number of problems and the patients' age. The problem types were classified according to a problem list. The results of this investigation suggest that greater attention must be paid to discussions about ethical problems among doctors and other categories of health personnel and that, among others, medical students ought to be taught the analysis of ethical problems. (shrink)

A total of 1918 loci, detected by the hybridization of 938 expressed sequence tag unigenes from 26 Triticeae cDNA libraries, were mapped to wheat homoeologous group 4 chromosomes using a set of deletion, ditelosomic, and nulli-tetrasomic lines. The 1918 EST loci were not distributed uniformly among the three group 4 chromosomes; 41, 28, and 31% mapped to chromosomes 4A, 4B, and 4D, respectively. This pattern is in contrast to the cumulative results of EST mapping in all homoeologous groups, as reported (...) elsewhere, that found the highest proportion of loci mapped to the B genome. Sixty-five percent of these 1918 loci mapped to the long arms of homoeologous group 4 chromosomes, while 35% mapped to the short arms. The distal regions of chromosome arms showed higher numbers of loci than the proximal regions, with the exception of 4DL. This study confirmed the complex structure of chromosome 4A that contains two reciprocal translocations and two inversions, previously identified. An additional inversion in the centromeric region of 4A was revealed. A consensus map for homoeologous group 4 was developed from 119 ESTs unique to group 4. Forty-nine percent of these ESTs were found to be homoologous to sequences on rice chromosome 3, 12% had matches with sequences on other rice chromosomes, and 39% had no matches with rice sequences at all. Limited homology was found between wheat ESTs on homoeologous group 4 and the Arabidopsis genome. Forty-two percent of the homoeologous group 4 ESTs could be classified into functional categories on the basis of blastX searches against all protein databases. (shrink)

Pancreatitis is a complex, progressively destructive inflammatory disorder. Alcohol was long thought to be the primary causative agent, but genetic contributions have been of interest since the discovery that rare PRSS1, CFTR and SPINK1 variants were associated with pancreatitis risk. We now report two associations at genome-wide significance identified and replicated at PRSS1-PRSS2 and X-linked CLDN2 through a two-stage genome-wide study. The PRSS1 variant likely affects disease susceptibility by altering expression of the primary trypsinogen gene. The CLDN2 risk allele is (...) associated with atypical localization of claudin-2 in pancreatic acinar cells. The homozygous CLDN2 genotype confers the greatest risk, and its alleles interact with alcohol consumption to amplify risk. These results could partially explain the high frequency of alcohol-related pancreatitis in men. © 2012 Nature America, Inc. All rights reserved. (shrink)

The objectives of this study were to develop a high-density chromosome bin map of homoeologous group 7 in hexaploid wheat, to identify gene distribution in these chromosomes, and to perform comparative studies of wheat with rice and barley. We mapped 2148 loci from 919 EST clones onto group 7 chromosomes of wheat. In the majority of cases the numbers of loci were significantly lower in the centromeric regions and tended to increase in the distal regions. The level of duplicated loci (...) in this group was 24% with most of these loci being localized toward the distal regions. One hundred nineteen EST probes that hybridized to three fragments and mapped to the three group 7 chromosomes were designated landmark probes and were used to construct a consensus homoeologous group 7 map. An additional 49 probes that mapped to 7AS, 7DS, and the ancestral translocated segment involving 7BS also were designated landmarks. Landmark probe orders and comparative maps of wheat, rice, and barley were produced on the basis of corresponding rice BAC/PAC and genetic markers that mapped on chromosomes 6 and 8 of rice. Identification of landmark ESTs and development of consensus maps may provide a framework of conserved coding regions predating the evolution of wheat genomes. (shrink)

New trends in the economic systems management in the context of modern global challenges: collective monograph / scientific edited by M. Bezpartochnyi, in 2 Vol. // VUZF University of Finance, Business and Entrepreneurship. – Sofia: VUZF Publishing House “St. Grigorii Bogoslov”, 2020. – Vol. 1. – 309 p.

Each contributor to this book has used personal experience as the basis from which to frame his individual sociological perspectives. Because they have personalized their work, their accounts are real, and recognizable as having come from 'real' persons, about 'real' experiences. There are no objectively-distanced disembodied third person entities in these accounts. These writers are actual people whose stories will make you laugh, cry, think, and want to know more.